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• It improves mitochondrial function and reduces oxidative stress in the brain.
• Maternal administration improves neurogenesis and cognitive function in prenatally stressed babies.
• It provides a protective effect against endothelial dysfunction in human aortic endothelial cells.
• Protective effects for acute inflammation and rheumatoid arthritis.
• It provides neuroprotection and cellular antioxidant defence, suggesting its potential pharmaceutical use for the treatment of neurodegenerative disorders.
• It ameliorates disturbances in white adipose tissue and plays a relevant metabolic and inflammatory function in overweight or obesity conditions.
• It is a bioactive compound that can counteract oxidative and inflammatory processes.
• It would ensure a less oxidative impact of chemotherapeutic drugs on breast cancer patients, which could potentially improve their well-being.
• Supplementation may be advantageous in rheumatoid arthritis.
• It reduces oxidative stress in the brain.
• Maternal administration improves cognitive function in prenatally stressed children.
• It reduces colon cancer growth.
• Hydroxytyrosol-cetuximab combination yields enhanced chemotherapeutic efficacy in colon cancer cells.
• It provides a basis for developing a new dietary strategy for the prevention of rheumatoid arthritis.
• It reduces oxidative DNA damage.
• It protects against damage to plasma.
• It prevents metabolic impairment reducing hepatic inflammation.
• It improves the main oxidative-stress parameters, insulin resistance and steatosis in children with non-alcoholic fatty liver disease (NAFLD).
• It has an antioxidant effect on human sperm quality.
• A basis for the creation of new pharmacological agents for cancer prevention and therapy.
• Cardioprotective effects of hydroxytyrosol by attenuation of metabolic risk factors.
• It ameliorates brain pathology and restores cognitive functions.
• It inhibits both enzymatic and spontaneous oxidation of endogenous dopamine and mitigates the increase in spontaneous oxidation during monoamine oxidase inhibition.
• It provides a cardioprotective effect against myocardial infarction.
• It increases vitamin C levels.
• It induces cell cycle arrest and apoptosis in colon cancer cells.
• It attenuates liver oxidative stress induced by a high-fat diet.
• Supplementation offers potential pharmacological and nutritional treatments.
• A potential candidate microbicide for preventing the transmission of AIDS (HIV-1) or curtailing its replication.
• For the treatment of prostate cancer.
• It is a therapeutic agent against thyroid cancer.
• It protects against ischemic injury.
• It exerts a neuroprotective effect on diabetic retinopathy.
• It protects against oxidative stress related to the nervous system.
• Neuroprotective effect in diabetes mellitus.
• It attenuates the initial steps of atherosclerosis.
• It reduces uric acid levels.
• It attenuates acute lung injury.
• It protects from bisphenol-A effects in livers and kidneys.
• Anti-inflammatory and antitumor effects
• Modulation of the immune system.
• It inhibits cancer stem cells and the metastatic capacity of triple-negative breast cancer cell lines.
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